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Research Article

Single-Molecule Dynamics Reveals Cooperative Binding-Folding in Protein Recognition

  • Jin Wang mail,

    To whom correspondence should be addressed. E-mail: jin.wang.1@stonybrook.edu (JW); peter.lu@pnl.gov (HPL)

    Affiliations: Department of Chemistry and Department of Physics, State University of New York at Stony Brook, Stony Brook, New York, United States of America, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, People's Republic of China

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  • Qiang Lu,

    Affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, People's Republic of China

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  • H. Peter Lu mail

    To whom correspondence should be addressed. E-mail: jin.wang.1@stonybrook.edu (JW); peter.lu@pnl.gov (HPL)

    Affiliation: Pacific Northwest National Laboratory, Fundamental Science Division, MSIN K8-88, Richland, Washington, United States of America

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  • Published: July 07, 2006
  • DOI: 10.1371/journal.pcbi.0020078

About the Authors

Jin Wang, Qiang Lu
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, People's Republic of China
Jin Wang
Department of Chemistry and Department of Physics, State University of New York at Stony Brook, Stony Brook, New York, United States of America
H. Peter Lu
Pacific Northwest National Laboratory, Fundamental Science Division, MSIN K8-88, Richland, Washington, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JW and PHL conceived and designed the experiments. QL performed the experiments. JW, QL, and PHL analyzed the data. JW, QL, and PHL contributed reagents/materials/analysis tools. JW and PHL wrote the paper.