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Research Article

Modeling Somatic Evolution in Tumorigenesis

  • Sabrina L Spencer equal contributor mail,

    equal contributor Contributed equally to this work with: Sabrina L Spencer, Ryan A Gerety

    To whom correspondence should be addressed. E-mail: spencers@mit.edu

    Affiliation: Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

    X
  • Ryan A Gerety equal contributor,

    equal contributor Contributed equally to this work with: Sabrina L Spencer, Ryan A Gerety

    Affiliation: Department of Computer Science, University of New Mexico, Albuquerque, New Mexico, United States of America

    X
  • Kenneth J Pienta,

    Affiliation: Department of Medical Oncology, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America

    X
  • Stephanie Forrest

    Affiliations: Department of Computer Science, University of New Mexico, Albuquerque, New Mexico, United States of America, Santa Fe Institute, Santa Fe, New Mexico, United States of America

    X
  • Published: August 18, 2006
  • DOI: 10.1371/journal.pcbi.0020108

About the Authors

Sabrina L Spencer
Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
Ryan A Gerety, Stephanie Forrest
Department of Computer Science, University of New Mexico, Albuquerque, New Mexico, United States of America
Kenneth J Pienta
Department of Medical Oncology, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
Stephanie Forrest
Santa Fe Institute, Santa Fe, New Mexico, United States of America

Corresponding Author

Email: spencers@mit.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SLS, RAG, KJP, and SF conceived and designed the experiments. SLS and RAG performed the experiments. SLS and RAG analyzed the data. RAG and SF contributed reagents/materials/analysis tools. SLS and RAG wrote the paper.