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Research Article

Model-Based Design of Growth-Attenuated Viruses

  • Kwang-il Lim,

    Affiliation: Department of Chemical and Biological Engineering, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    ¤a Current address: Department of Chemical Engineering and The Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, California, United States of America

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  • Tobias Lang,

    Affiliation: Department of Chemical and Biological Engineering, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    ¤b Current address: Institut für Mechanische Verfahrenstechnik, Universität Stuttgart, Stuttgart, Germany

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  • Vy Lam,

    Affiliation: Department of Chemical and Biological Engineering, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

    ¤c Current address: Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America

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  • John Yin mail

    To whom correspondence should be addressed. E-mail: yin@engr.wisc.edu

    Affiliation: Department of Chemical and Biological Engineering, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

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  • Published: September 01, 2006
  • DOI: 10.1371/journal.pcbi.0020116

About the Authors

Kwang-il Lim, Tobias Lang, Vy Lam, John Yin
Department of Chemical and Biological Engineering, University of Wisconsin–Madison, Madison, Wisconsin, United States of America

Corresponding Author

Email: yin@engr.wisc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

KL, TL, and VL conceived and designed the experiments. KL and VL performed the experiments. KL, VL, and JY analyzed the data. KL, TL, and VL contributed reagents/materials/analysis tools. KL, VL, and JY wrote the paper.