About the Authors

Alan M Moses

Affiliation Graduate Group in Biophysics, University of California Berkeley, Berkeley, California, United States of America

Daniel A Pollard

Affiliation Graduate Group in Biophysics, University of California Berkeley, Berkeley, California, United States of America

David A Nix

Affiliation Department of Genome Sciences, Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

Venky N Iyer

Affiliation Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America

Xiao-Yong Li

Affiliation Department of Genome Sciences, Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

Mark D Biggin

Affiliation Department of Genome Sciences, Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America

Michael B Eisen

To whom correspondence should be addressed. E-mail: mbeisen@lbl.gov

Affiliations Graduate Group in Biophysics, University of California Berkeley, Berkeley, California, United States of America , Department of Genome Sciences, Genomics Division, Ernest Orlando Lawrence Berkeley National Lab, Berkeley, California, United States of America , Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America , Center for Integrative Genomics, University of California Berkeley, Berkeley, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

AMM and MBE conceived and designed the experiments. AMM, DAP, and XYL performed the experiments. AMM and DAP analyzed the data. AMM, DAP, DAN, VNI, XYL, and MDB contributed reagents/materials/analysis tools. AMM, MBE, DAP, and DAN wrote the paper.