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Research Article

The Role of Compensatory Mutations in the Emergence of Drug Resistance

  • Andreas Handel mail,

    To whom correspondence should be addressed. E-mail: ahandel@emory.edu

    Affiliation: Department of Biology, Emory University, Atlanta, Georgia, United States of America

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  • Roland R Regoes,

    Affiliation: Department of Biology, Emory University, Atlanta, Georgia, United States of America

    ¤ Current address: Theoretical Biology, Swiss Federal Institute of Technology, Zurich, Switzerland

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  • Rustom Antia

    Affiliation: Department of Biology, Emory University, Atlanta, Georgia, United States of America

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  • Published: October 13, 2006
  • DOI: 10.1371/journal.pcbi.0020137

About the Authors

Andreas Handel, Roland R Regoes, Rustom Antia
Department of Biology, Emory University, Atlanta, Georgia, United States of America

Corresponding Author

Email: ahandel@emory.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

AH, RRR, and RA conceived and designed the study. AH performed the analysis and simulations and analyzed the data. RRR contributed analysis tools. AH, RRR, and RA wrote the paper.