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Research Article

Modeling HER2 Effects on Cell Behavior from Mass Spectrometry Phosphotyrosine Data

  • Neil Kumar,

    Affiliation: Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Alejandro Wolf-Yadlin,

    Affiliation: Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Forest M White,

    Affiliations: Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Douglas A Lauffenburger mail

    To whom correspondence should be addressed. E-mail: lauffen@mit.edu

    Affiliations: Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Published: January 05, 2007
  • DOI: 10.1371/journal.pcbi.0030004

About the Authors

Neil Kumar, Douglas A Lauffenburger
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
Alejandro Wolf-Yadlin, Forest M White, Douglas A Lauffenburger
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
Forest M White, Douglas A Lauffenburger
Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Corresponding Author

Email: lauffen@mit.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

NK, AWY, FMW, and DAL conceived and designed the experiments. NK performed the experiments and analyzed the data. NK, AWY, FW, and DAL wrote the paper.