About the Authors

Lawrence C Lee

Affiliations Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, United States of America , Biomedical Informatics, University of California San Francisco, San Francisco, California, United States of America

Florence Horn

Affiliation Laboratoire de Biologie, Informatique et Mathématiques, Commissariat à l'Energie Atomique, Grenoble, France

Fred E Cohen

To whom correspondence should be addressed. E-mail: cohen@cmpharm.ucsf.edu

Affiliations Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California, United States of America , Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

LCL wrote Mutation GraB, designed the experiments, carried out the analysis, read and manually annotated the literature sets, and drafted the manuscript. FH conceived of the study and contributed to the methods. FEC helped conceive the study and helped draft the manuscript.