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Research Article

Frequent Gain and Loss of Functional Transcription Factor Binding Sites

  • Scott W Doniger,

    Affiliation: Computational Biology Program, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Justin C Fay mail

    To whom correspondence should be addressed. E-mail: jfay@genetics.wustl.edu

    Affiliations: Computational Biology Program, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Published: May 25, 2007
  • DOI: 10.1371/journal.pcbi.0030099

About the Authors

Scott W Doniger, Justin C Fay
Computational Biology Program, Washington University School of Medicine, St. Louis, Missouri, United States of America
Justin C Fay
Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Corresponding Author

Email: jfay@genetics.wustl.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SWD and JCF conceived and designed the experiments. SWD performed the experiments, analyzed the data, and wrote the paper.