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Research Article

A Mass Conserved Reaction–Diffusion System Captures Properties of Cell Polarity

  • Mikiya Otsuji mail,

    To whom correspondence should be addressed. E-mail: mohtsuji-tky@umin.ac.jp

    Affiliation: Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo, Japan

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  • Shuji Ishihara,

    Affiliation: Division of Theoretical Biology, National Institute for Basic Biology, Okazaki, Japan

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  • Carl Co,

    Affiliation: Department of Cellular and Molecular Pharmacology and Program in Biological Sciences, University of California San Francisco, San Francisco, California, United States of America

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  • Kozo Kaibuchi,

    Affiliation: Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, Nagoya, Japan

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  • Atsushi Mochizuki,

    Affiliation: Division of Theoretical Biology, National Institute for Basic Biology, Okazaki, Japan

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  • Shinya Kuroda

    Affiliation: Department of Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, Tokyo, Japan

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  • Published: June 08, 2007
  • DOI: 10.1371/journal.pcbi.0030108

About the Authors

Mikiya Otsuji
Department of Anesthesiology, Faculty of Medicine, University of Tokyo, Tokyo, Japan
Shuji Ishihara, Atsushi Mochizuki
Division of Theoretical Biology, National Institute for Basic Biology, Okazaki, Japan
Carl Co
Department of Cellular and Molecular Pharmacology and Program in Biological Sciences, University of California San Francisco, San Francisco, California, United States of America
Kozo Kaibuchi
Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, Nagoya, Japan
Shinya Kuroda
Department of Biophysics and Biochemistry, Graduate School of Science, University of Tokyo, Tokyo, Japan

Corresponding Author

Email: mohtsuji-tky@umin.ac.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MO, SI, CC, KK, AM, and SK conceived and designed the experiments. MO performed the experiments. MO and SI analyzed the data. MO, SI, CC, KK, AM, and SK wrote the paper.