The Effect of Stochasticity on the Lac Operon: An Evolutionary Perspective

Open Access

Peer-reviewed

Research Article

Milan van Hoek ,

*To whom correspondence should be addressed. E-mail: M.J.A.vanHoek@bio.uu.nl

Affiliation Theoretical Biology/Bioinformatics Group, Utrecht University, Utrecht, The Netherlands
⨯
Paulien Hogeweg

Affiliation Theoretical Biology/Bioinformatics Group, Utrecht University, Utrecht, The Netherlands
⨯

About the Authors

Milan van Hoek

*To whom correspondence should be addressed. E-mail: M.J.A.vanHoek@bio.uu.nl

Affiliation Theoretical Biology/Bioinformatics Group, Utrecht University, Utrecht, The Netherlands

Paulien Hogeweg

Affiliation Theoretical Biology/Bioinformatics Group, Utrecht University, Utrecht, The Netherlands

The authors have declared that no competing interests exist.

MvH and PH conceived and designed the model. MvH performed the simulations. Both authors contributed to writing the paper.

Lactose
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Gene expression
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lac operon
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Glucose
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Evolutionary genetics
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Operons
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Biochemical simulations
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Cell cycle and cell division
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