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Research Article

Flexible and Accurate Detection of Genomic Copy-Number Changes from aCGH

  • Oscar M Rueda mail,

    To whom correspondence should be addressed. E-mail: omrueda@cnio.es (OMR), rdiaz02@gmail.com (RDU)

    Affiliation: Structural and Computational Biology Programme, Spanish National Cancer Centre (CNIO), Madrid, Spain

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  • Ramón Díaz-Uriarte mail

    To whom correspondence should be addressed. E-mail: omrueda@cnio.es (OMR), rdiaz02@gmail.com (RDU)

    Affiliation: Structural and Computational Biology Programme, Spanish National Cancer Centre (CNIO), Madrid, Spain

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  • Published: June 22, 2007
  • DOI: 10.1371/journal.pcbi.0030122

About the Authors

Oscar M Rueda, Ramón Díaz-Uriarte
Structural and Computational Biology Programme, Spanish National Cancer Centre (CNIO), Madrid, Spain

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

OMR developed the statistical model, did most of the programming, and conducted analysis. RDU conceived the model, participated in model development and programming, and conducted simulations. Both authors wrote the paper.