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Research Article

Mechanisms of Firing Patterns in Fast-Spiking Cortical Interneurons

  • David Golomb mail,

    To whom correspondence should be addressed. E-mail: golomb@bgu.ac.il

    Affiliations: Department of Physiology, Ben-Gurion University, Be'er-Sheva, Israel, Zlotowski Center for Neuroscience, Ben-Gurion University, Be'er-Sheva, Israel

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  • Karnit Donner,

    Affiliations: Department of Physiology, Ben-Gurion University, Be'er-Sheva, Israel, Zlotowski Center for Neuroscience, Ben-Gurion University, Be'er-Sheva, Israel

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  • Liron Shacham,

    Affiliations: Department of Physiology, Ben-Gurion University, Be'er-Sheva, Israel, Zlotowski Center for Neuroscience, Ben-Gurion University, Be'er-Sheva, Israel

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  • Dan Shlosberg,

    Affiliations: Department of Physiology, Ben-Gurion University, Be'er-Sheva, Israel, Zlotowski Center for Neuroscience, Ben-Gurion University, Be'er-Sheva, Israel

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  • Yael Amitai,

    Affiliations: Department of Physiology, Ben-Gurion University, Be'er-Sheva, Israel, Zlotowski Center for Neuroscience, Ben-Gurion University, Be'er-Sheva, Israel

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  • David Hansel

    Affiliations: Laboratory of Neurophysics and Physiology, Université Paris René Descartes, Paris, France, CNRS UMR 8119, Paris, France, Franco-Israeli Laboratory of Neurophysics and System Physiology, Université Paris René Descartes, Paris, France

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  • Published: August 10, 2007
  • DOI: 10.1371/journal.pcbi.0030156

About the Authors

David Golomb, Karnit Donner, Liron Shacham, Dan Shlosberg, Yael Amitai
Department of Physiology, Ben-Gurion University, Be'er-Sheva, Israel
David Golomb, Karnit Donner, Liron Shacham, Dan Shlosberg, Yael Amitai
Zlotowski Center for Neuroscience, Ben-Gurion University, Be'er-Sheva, Israel
David Hansel
Laboratory of Neurophysics and Physiology, Université Paris René Descartes, Paris, France
David Hansel
CNRS UMR 8119, Paris, France
David Hansel
Franco-Israeli Laboratory of Neurophysics and System Physiology, Université Paris René Descartes, Paris, France

Corresponding Author

Email: golomb@bgu.ac.il

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

DG constructed the model and the theory and analyzed the data. DG and DH formulated the research questions. DG, KD, and LS performed the simulations and the bifurcation calculations. DS and YA performed the experiments. DG, DH, and YA wrote the paper.