About the Authors

Anna Lobley

Affiliation Bioinformatics Unit, Department of Computer Science, University College London, London, United Kingdom

Mark B Swindells

Affiliation Inpharmatica, London, United Kingdom

Christine A Orengo

Affiliation Biocomputing Group, Department of Biochemistry, University College London, London, United Kingdom

David T Jones

To whom correspondence should be addressed. E-mail: d.jones@cs.ucl.ac.uk

Affiliations Bioinformatics Unit, Department of Computer Science, University College London, London, United Kingdom , Biocomputing Group, Department of Biochemistry, University College London, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

DTJ conceived and designed the experiments. AL analyzed the data, contributed reagents/materials/analysis tools, and wrote the paper. MBS and CAO critically reviewed the manuscript and provided helpful discussion throughout.