About the Authors

Doron Betel

To whom correspondence should be addressed. E-mail: betel@cbio.mskcc.org

¤ Current address: Computational and Systems Biology Center, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Affiliations Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada , Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

Kevin E Breitkreuz

Affiliation Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada

Ruth Isserlin

Affiliations Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada , Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

Danielle Dewar-Darch

Affiliation Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada

Mike Tyers

Affiliations Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada , Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario, Canada

Christopher W. V Hogue

Affiliation Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

DB and MT conceived and designed the experiments and wrote the paper. KEB and DDD performed the experiments. DB and RI analyzed the data. RI contributed reagents/materials/analysis tools. DB conceived and designed the project, and performed the computational work. MT and CWVH directed the study.