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Research Article

Comparative Genomics Search for Losses of Long-Established Genes on the Human Lineage

  • Jingchun Zhu,

    Affiliation: Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America

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  • J. Zachary Sanborn,

    Affiliation: Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America

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  • Mark Diekhans,

    Affiliation: Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America

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  • Craig B Lowe,

    Affiliation: Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America

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  • Tom H Pringle,

    Affiliation: Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America

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  • David Haussler mail

    To whom correspondence should be addressed. E-mail: haussler@soe.ucsc.edu

    Affiliations: Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America, Howard Hughes Medical Institute, University of California Santa Cruz, Santa Cruz, California, United States of America

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  • Published: December 14, 2007
  • DOI: 10.1371/journal.pcbi.0030247

About the Authors

Jingchun Zhu, J. Zachary Sanborn, Mark Diekhans, Craig B Lowe, Tom H Pringle, David Haussler
Center for Biomolecular Science and Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America
David Haussler
Howard Hughes Medical Institute, University of California Santa Cruz, Santa Cruz, California, United States of America

Corresponding Author

Email: haussler@soe.ucsc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JZ and DH conceived and designed the experiments. JZ, JZS, MD, and CBL performed the experiments. JZ, JZS, and THP analyzed the data. JZ, JZS, and MD contributed reagents/materials/analysis tools. JZ, JZS, and DH wrote the paper.