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Research Article

Animal Cell Differentiation Patterns Suppress Somatic Evolution

  • John W Pepper mail,

    To whom correspondence should be addressed. E-mail: jpepper1@email.arizona.edu

    Affiliations: Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, United States of America, The Santa Fe Institute, Santa Fe, New Mexico, United States of America

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  • Kathleen Sprouffske,

    Affiliations: Genomics and Computational Biology Program, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Systems Biology Division, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

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  • Carlo C Maley

    Affiliation: Systems Biology Division, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

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  • Published: December 14, 2007
  • DOI: 10.1371/journal.pcbi.0030250

About the Authors

John W Pepper
Department of Ecology and Evolutionary Biology, University of Arizona, Tucson, Arizona, United States of America
John W Pepper
The Santa Fe Institute, Santa Fe, New Mexico, United States of America
Kathleen Sprouffske
Genomics and Computational Biology Program, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Kathleen Sprouffske, Carlo C Maley
Systems Biology Division, The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: jpepper1@email.arizona.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JWP and CCM conceived and designed the experiments. JWP, KS, and CCM performed the experiments. JWP, KS, and CCM analyzed the data. JWP and CCM wrote the paper.