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Research Article

Sequence Similarity Network Reveals Common Ancestry of Multidomain Proteins

  • Nan Song,

    Affiliation: Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

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  • Jacob M. Joseph,

    Affiliation: Computational Biology, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

    X
  • George B. Davis,

    Affiliation: School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

    X
  • Dannie Durand mail

    durand@cmu.edu

    Affiliations: Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America, School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

    X
  • Published: May 16, 2008
  • DOI: 10.1371/journal.pcbi.1000063

About the Authors

Nan Song, Dannie Durand
Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
Jacob M. Joseph
Computational Biology, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
George B. Davis, Dannie Durand
School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

Corresponding Author

Email: durand@cmu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NS JJ DD. Performed the experiments: NS JJ GD. Analyzed the data: NS JJ GD DD. Contributed reagents/materials/analysis tools: JJ GD. Wrote the paper: NS JJ GD DD.