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Research Article

Performance and Scalability of Discriminative Metrics for Comparative Gene Identification in 12 Drosophila Genomes

  • Michael F. Lin,

    Affiliation: Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, United States of America

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  • Ameya N. Deoras,

    Affiliation: Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Matthew D. Rasmussen,

    Affiliation: Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Manolis Kellis mail

    manoli@mit.edu

    Affiliations: Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, United States of America, Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Published: April 18, 2008
  • DOI: 10.1371/journal.pcbi.1000067

About the Authors

Michael F. Lin, Manolis Kellis
Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, United States of America
Ameya N. Deoras, Matthew D. Rasmussen, Manolis Kellis
Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Corresponding Author

Email: manoli@mit.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ML AD MK. Performed the experiments: ML AD. Analyzed the data: ML AD. Contributed reagents/materials/analysis tools: ML AD MR. Wrote the paper: ML MK.