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Research Article

An Allosteric Mechanism for Switching between Parallel Tracks in Mammalian Sulfur Metabolism

  • Tatyana K. Korendyaseva equal contributor,

    equal contributor Contributed equally to this work with: Tatyana K. Korendyaseva, Denis N. Kuvatov

    Affiliation: National Research Center for Hematology, RAMS, Moscow, Russia

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  • Denis N. Kuvatov equal contributor,

    equal contributor Contributed equally to this work with: Tatyana K. Korendyaseva, Denis N. Kuvatov

    Affiliation: National Research Center for Hematology, RAMS, Moscow, Russia

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  • Vladimir A. Volkov,

    Affiliation: National Research Center for Hematology, RAMS, Moscow, Russia

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  • Michael V. Martinov,

    Affiliation: National Research Center for Hematology, RAMS, Moscow, Russia

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  • Victor M. Vitvitsky,

    Affiliations: National Research Center for Hematology, RAMS, Moscow, Russia, Biological Chemistry Department, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Ruma Banerjee,

    Affiliation: Biological Chemistry Department, University of Michigan, Ann Arbor, Michigan, United States of America

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  • Fazoil I. Ataullakhanov mail

    fazly@hc.comcor.ru

    Affiliations: National Research Center for Hematology, RAMS, Moscow, Russia, Department of Physics, Moscow State University, Moscow, Russia, Center for Theoretical Problems of Physicochemical Pharmacology, RAS, Moscow, Russia

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  • Published: May 02, 2008
  • DOI: 10.1371/journal.pcbi.1000076

About the Authors

Tatyana K. Korendyaseva, Denis N. Kuvatov, Vladimir A. Volkov, Michael V. Martinov, Victor M. Vitvitsky, Fazoil I. Ataullakhanov
National Research Center for Hematology, RAMS, Moscow, Russia
Victor M. Vitvitsky, Ruma Banerjee
Biological Chemistry Department, University of Michigan, Ann Arbor, Michigan, United States of America
Fazoil I. Ataullakhanov
Department of Physics, Moscow State University, Moscow, Russia
Fazoil I. Ataullakhanov
Center for Theoretical Problems of Physicochemical Pharmacology, RAS, Moscow, Russia

Corresponding Author

Email: fazly@hc.comcor.ru

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VMV FA. Performed the experiments: TK DK VAV MM. Analyzed the data: TK DK MM VMV RB FA. Wrote the paper: MM VMV RB FA.