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Research Article

Coordinate Regulation of G Protein Signaling via Dynamic Interactions of Receptor and GAP

  • Marc Turcotte,

    Affiliation: Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Wei Tang,

    Affiliations: Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America, Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Elliott M. Ross mail

    ross@utsw.swmed.edu

    Affiliation: Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Published: August 15, 2008
  • DOI: 10.1371/journal.pcbi.1000148

About the Authors

Marc Turcotte, Wei Tang, Elliott M. Ross
Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
Wei Tang
Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Corresponding Author

Email: ross@utsw.swmed.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WT EMR. Performed the experiments: WT. Analyzed the data: MT EMR. Contributed reagents/materials/analysis tools: EMR. Wrote the paper: MT EMR. Performed computational analyses, fitting, and simulations: MT.