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Research Article

Discarding Functional Residues from the Substitution Table Improves Predictions of Active Sites within Three-Dimensional Structures

  • Sungsam Gong,

    Affiliation: Biocomputing Group, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

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  • Tom L. Blundell mail

    tom@cryst.bioc.cam.ac.uk

    Affiliation: Biocomputing Group, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

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  • Published: October 03, 2008
  • DOI: 10.1371/journal.pcbi.1000179

About the Authors

Sungsam Gong, Tom L. Blundell
Biocomputing Group, Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

Corresponding Author

Email: tom@cryst.bioc.cam.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SG TLB. Performed the experiments: SG. Analyzed the data: SG TLB. Wrote the paper: SG TLB.