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Research Article

Biophysical Basis for Three Distinct Dynamical Mechanisms of Action Potential Initiation

  • Steven A. Prescott mail,

    prescott@neurobio.pitt.edu

    Affiliations: Computational Neurobiology Laboratory, Salk Institute, La Jolla, California, United States of America, Howard Hughes Medical Institute, La Jolla, California, United States of America

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  • Yves De Koninck,

    Affiliation: Division de Neurobiologie Cellulaire, Centre de Recherche Université Laval Robert-Giffard, Québec, Québec, Canada

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  • Terrence J. Sejnowski

    Affiliations: Computational Neurobiology Laboratory, Salk Institute, La Jolla, California, United States of America, Howard Hughes Medical Institute, La Jolla, California, United States of America, Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

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  • Published: October 10, 2008
  • DOI: 10.1371/journal.pcbi.1000198

About the Authors

Steven A. Prescott, Terrence J. Sejnowski
Computational Neurobiology Laboratory, Salk Institute, La Jolla, California, United States of America
Steven A. Prescott, Terrence J. Sejnowski
Howard Hughes Medical Institute, La Jolla, California, United States of America
Yves De Koninck
Division de Neurobiologie Cellulaire, Centre de Recherche Université Laval Robert-Giffard, Québec, Québec, Canada
Terrence J. Sejnowski
Division of Biological Sciences, University of California San Diego, La Jolla, California, United States of America

Corresponding Author

Email: prescott@neurobio.pitt.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SAP YDK TJS. Performed the experiments: SAP. Analyzed the data: SAP. Wrote the paper: SAP YDK TJS.