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Research Article

Age-Dependent Evolution of the Yeast Protein Interaction Network Suggests a Limited Role of Gene Duplication and Divergence

  • Wan Kyu Kim,

    Affiliation: Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America

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  • Edward M. Marcotte mail

    marcotte@icmb.utexas.edu

    Affiliation: Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America

    X
  • Published: November 28, 2008
  • DOI: 10.1371/journal.pcbi.1000232

About the Authors

Wan Kyu Kim, Edward M. Marcotte
Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America

Corresponding Author

Email: marcotte@icmb.utexas.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WKK EMM. Performed the experiments: WKK. Analyzed the data: WKK EMM. Contributed reagents/materials/analysis tools: WKK. Wrote the paper: WKK EMM.