Advertisement
Research Article

Steady-State Kinetic Modeling Constrains Cellular Resting States and Dynamic Behavior

  • Jeremy E. Purvis,

    Affiliations: Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Genomics and Computational Biology Program, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Ravi Radhakrishnan,

    Affiliation: Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Scott L. Diamond mail

    sld@seas.upenn.edu

    Affiliations: Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

    X
  • Published: March 06, 2009
  • DOI: 10.1371/journal.pcbi.1000298

About the Authors

Jeremy E. Purvis, Scott L. Diamond
Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Jeremy E. Purvis
Genomics and Computational Biology Program, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Ravi Radhakrishnan
Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
Scott L. Diamond
Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: sld@seas.upenn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JEP RR SLD. Performed the experiments: JEP. Analyzed the data: JEP RR SLD. Wrote the paper: JEP RR SLD.