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Research Article

Alu Exonization Events Reveal Features Required for Precise Recognition of Exons by the Splicing Machinery

  • Schraga Schwartz,

    Affiliation: Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel

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  • Nurit Gal-Mark,

    Affiliation: Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel

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  • Nir Kfir,

    Affiliation: Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel

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  • Ram Oren,

    Affiliation: Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel

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  • Eddo Kim,

    Affiliation: Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel

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  • Gil Ast mail

    gilast@post.tau.ac.il

    Affiliation: Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel

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  • Published: March 06, 2009
  • DOI: 10.1371/journal.pcbi.1000300

About the Authors

Schraga Schwartz, Nurit Gal-Mark, Nir Kfir, Ram Oren, Eddo Kim, Gil Ast
Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel

Corresponding Author

Email: gilast@post.tau.ac.il

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SS NGM RO GA. Performed the experiments: SS. Analyzed the data: SS. Contributed reagents/materials/analysis tools: SS NGM NK EK. Wrote the paper: SS NGM NK RO GA.