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Research Article

Using Network Component Analysis to Dissect Regulatory Networks Mediated by Transcription Factors in Yeast

  • Chun Ye mail,

    cye@bioinf.ucsd.edu

    Affiliation: Bioinformatics Program, University of California San Diego, La Jolla, California, United States of America

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  • Simon J. Galbraith,

    Affiliation: Department of Computer Science, University of California Los Angeles, Los Angeles, California, United States of America

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  • James C. Liao,

    Affiliation: Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, United States of America

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  • Eleazar Eskin

    Affiliations: Department of Computer Science, University of California Los Angeles, Los Angeles, California, United States of America, Department of Human Genetics, University of California Los Angeles, Los Angeles, California, United States of America

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  • Published: March 20, 2009
  • DOI: 10.1371/journal.pcbi.1000311

About the Authors

Chun Ye
Bioinformatics Program, University of California San Diego, La Jolla, California, United States of America
Simon J. Galbraith, Eleazar Eskin
Department of Computer Science, University of California Los Angeles, Los Angeles, California, United States of America
James C. Liao
Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, United States of America
Eleazar Eskin
Department of Human Genetics, University of California Los Angeles, Los Angeles, California, United States of America

Corresponding Author

Email: cye@bioinf.ucsd.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CY SJG EE. Performed the experiments: CY. Analyzed the data: CY. Contributed reagents/materials/analysis tools: CY SJG JCL. Wrote the paper: CY SJG JCL EE.