About the Authors

Ines Thiele

Affiliations Ph.D. Program in Bioinformatics, University of California San Diego, La Jolla, California, United States of America, Systems Biology Research Group, Bioengineering Department, University of California San Diego, La Jolla, California, United States of America

Neema Jamshidi

Affiliation Systems Biology Research Group, Bioengineering Department, University of California San Diego, La Jolla, California, United States of America

Ronan M. T. Fleming

Affiliation Systems Biology Research Group, Bioengineering Department, University of California San Diego, La Jolla, California, United States of America

Bernhard Ø. Palsson

bpalsson@bioeng.ucsd.edu

Affiliation Systems Biology Research Group, Bioengineering Department, University of California San Diego, La Jolla, California, United States of America

Competing Interests

The principal investigator and UCSD have a financial interest in Genomatica, Inc., although this grant has been identified for conflict of interest management based on the overall scope of the project and its potential to benefit Genomatica, Inc, the research findings included in this publication may not necessarily directly relate to the interests of Genomatica, Inc.

Author Contributions

Conceived and designed the experiments: IT NJ RMTF BP. Performed the experiments: IT. Analyzed the data: IT NJ RMTF BP. Contributed reagents/materials/analysis tools: IT. Wrote the paper: IT NJ RMTF BP.