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Research Article

The Homeostasis of Plasmodium falciparum-Infected Red Blood Cells

  • Jakob M. A. Mauritz,

    Affiliations: Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom

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  • Alessandro Esposito mail,

    aesposito@quantitative-microscopy.org

    Affiliations: Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom

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  • Hagai Ginsburg,

    Affiliation: Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University, Jerusalem, Israel

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  • Clemens F. Kaminski,

    Affiliations: Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom, School of Advanced Optical Technologies, Max-Planck-Research Group, Division III, University of Erlangen-Nuremberg, Erlangen, Germany

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  • Teresa Tiffert,

    Affiliation: Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom

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  • Virgilio L. Lew

    Affiliation: Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom

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  • Published: April 03, 2009
  • DOI: 10.1371/journal.pcbi.1000339

About the Authors

Jakob M. A. Mauritz, Alessandro Esposito, Clemens F. Kaminski
Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom
Jakob M. A. Mauritz, Alessandro Esposito, Teresa Tiffert, Virgilio L. Lew
Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
Hagai Ginsburg
Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University, Jerusalem, Israel
Clemens F. Kaminski
School of Advanced Optical Technologies, Max-Planck-Research Group, Division III, University of Erlangen-Nuremberg, Erlangen, Germany

Corresponding Author

Email: aesposito@quantitative-microscopy.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VLL. Performed the experiments: JMAM. Analyzed the data: JMAM. Wrote the paper: JMAM AE VLL. Adapted the original software for the numerical simulations: JMAM AE VLL. Contributed with model design, analysis of model simulations, formulation of the colloid-osmotic hypothesis, and editing of the manuscript: HG CFK TT.