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Research Article

Allosteric Transitions of Supramolecular Systems Explored by Network Models: Application to Chaperonin GroEL

  • Zheng Yang,

    Affiliations: Department of Computational Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Physics and Astronomy, School of Arts & Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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  • Peter Májek,

    Affiliation: Department of Computer Science, Cornell University, Ithaca, New York, United States of America

    X
  • Ivet Bahar mail

    bahar@ccbb.pitt.edu

    Affiliation: Department of Computational Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

    X
  • Published: April 17, 2009
  • DOI: 10.1371/journal.pcbi.1000360

About the Authors

Zheng Yang, Ivet Bahar
Department of Computational Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
Zheng Yang
Department of Physics and Astronomy, School of Arts & Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
Peter Májek
Department of Computer Science, Cornell University, Ithaca, New York, United States of America

Corresponding Author

Email: bahar@ccbb.pitt.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZY IB. Performed the experiments: ZY PM. Analyzed the data: ZY PM IB. Wrote the paper: ZY IB.