About the Authors

Srinivas Ramachandran

Affiliations Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America, Molecular and Cellular Biophysics Program, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

Adrian W. R. Serohijos

Affiliations Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America, Molecular and Cellular Biophysics Program, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Physics and Astronomy, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

Le Xu

Affiliation Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

Gerhard Meissner

Affiliations Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America, Molecular and Cellular Biophysics Program, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

Nikolay V. Dokholyan

dokh@med.unc.edu

Affiliations Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America, Molecular and Cellular Biophysics Program, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SR AWRS LX GM NVD. Performed the experiments: SR AWRS LX GM NVD. Analyzed the data: SR AWRS LX GM NVD. Wrote the paper: SR AWRS LX GM NVD.