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Research Article

Computational Models of the Notch Network Elucidate Mechanisms of Context-dependent Signaling

  • Smita Agrawal,

    Affiliations: Department of Chemical Engineering, University of California Berkeley, Berkeley, California, United States of America, Department of Bioengineering, University of California Berkeley, Berkeley, California, United States of America, Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, California, United States of America

    Current address: Institute of Human Genetics, University of Minnesota Twin Cities, Minneapolis, Minnesota, United States of America

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  • Colin Archer,

    Affiliations: Department of Chemical Engineering, University of California Berkeley, Berkeley, California, United States of America, Department of Bioengineering, University of California Berkeley, Berkeley, California, United States of America, Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, California, United States of America

    Current address: Australian Institute of Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Australia

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  • David V. Schaffer mail

    schaffer@berkeley.edu

    Affiliations: Department of Chemical Engineering, University of California Berkeley, Berkeley, California, United States of America, Department of Bioengineering, University of California Berkeley, Berkeley, California, United States of America, Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, California, United States of America

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  • Published: May 22, 2009
  • DOI: 10.1371/journal.pcbi.1000390

About the Authors

Smita Agrawal, Colin Archer, David V. Schaffer
Department of Chemical Engineering, University of California Berkeley, Berkeley, California, United States of America
Smita Agrawal, Colin Archer, David V. Schaffer
Department of Bioengineering, University of California Berkeley, Berkeley, California, United States of America
Smita Agrawal, Colin Archer, David V. Schaffer
Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, California, United States of America

Corresponding Author

Email: schaffer@berkeley.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SA DVS. Performed the experiments: SA. Analyzed the data: SA. Contributed reagents/materials/analysis tools: SA CA. Wrote the paper: SA.