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Research Article

Understanding the Adaptive Growth Strategy of Lactobacillus plantarum by In Silico Optimisation

  • Bas Teusink mail,

    bas.teusink@falw.vu.nl

    Affiliations: Top Institute Food and Nutrition (WCFS), Wageningen, The Netherlands, NIZO Food Research BV, Ede, The Netherlands, Center for Molecular and Biomolecular Informatics (NCMLS), Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands, Kluyver Centre for Genomics of Industrial Fermentation, Delft, The Netherlands

    Current address: IBIVU Systems Bioinformatics, Amsterdam, The Netherlands

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  • Anne Wiersma,

    Affiliations: Top Institute Food and Nutrition (WCFS), Wageningen, The Netherlands, NIZO Food Research BV, Ede, The Netherlands, Kluyver Centre for Genomics of Industrial Fermentation, Delft, The Netherlands

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  • Leo Jacobs,

    Affiliations: Top Institute Food and Nutrition (WCFS), Wageningen, The Netherlands, NIZO Food Research BV, Ede, The Netherlands

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  • Richard A. Notebaart,

    Affiliations: Center for Molecular and Biomolecular Informatics (NCMLS), Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands, Kluyver Centre for Genomics of Industrial Fermentation, Delft, The Netherlands

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  • Eddy J. Smid

    Affiliations: Top Institute Food and Nutrition (WCFS), Wageningen, The Netherlands, NIZO Food Research BV, Ede, The Netherlands, Kluyver Centre for Genomics of Industrial Fermentation, Delft, The Netherlands

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  • Published: June 12, 2009
  • DOI: 10.1371/journal.pcbi.1000410

About the Authors

Bas Teusink, Anne Wiersma, Leo Jacobs, Eddy J. Smid
Top Institute Food and Nutrition (WCFS), Wageningen, The Netherlands
Bas Teusink, Anne Wiersma, Leo Jacobs, Eddy J. Smid
NIZO Food Research BV, Ede, The Netherlands
Bas Teusink, Richard A. Notebaart
Center for Molecular and Biomolecular Informatics (NCMLS), Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Bas Teusink, Anne Wiersma, Richard A. Notebaart, Eddy J. Smid
Kluyver Centre for Genomics of Industrial Fermentation, Delft, The Netherlands

Corresponding Author

Email: bas.teusink@falw.vu.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BT AW LJ RAN EJS. Performed the experiments: AW LJ. Analyzed the data: BT AW LJ RAN. Contributed reagents/materials/analysis tools: RAN. Wrote the paper: BT AW RAN EJS.