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Research Article

Identification of a Topological Characteristic Responsible for the Biological Robustness of Regulatory Networks

  • Yangle Wu,

    Affiliations: Center for Theoretical Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, People's Republic of China, The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics, Peking University, Beijing, People's Republic of China

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  • Xiaomeng Zhang,

    Affiliations: Center for Theoretical Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, People's Republic of China, The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics, Peking University, Beijing, People's Republic of China

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  • Jianglei Yu,

    Affiliations: Center for Theoretical Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, People's Republic of China, The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics, Peking University, Beijing, People's Republic of China

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  • Qi Ouyang mail

    qi@pku.edu.cn

    Affiliations: Center for Theoretical Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, People's Republic of China, The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics, Peking University, Beijing, People's Republic of China, Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong, Special Administrative Region, People's Republic of China

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  • Published: July 24, 2009
  • DOI: 10.1371/journal.pcbi.1000442

About the Authors

Yangle Wu, Xiaomeng Zhang, Jianglei Yu, Qi Ouyang
Center for Theoretical Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, People's Republic of China
Yangle Wu, Xiaomeng Zhang, Jianglei Yu, Qi Ouyang
The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics, Peking University, Beijing, People's Republic of China
Qi Ouyang
Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong, Special Administrative Region, People's Republic of China

Corresponding Author

Email: qi@pku.edu.cn

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YW QO. Performed the experiments: YW XZ JY. Analyzed the data: YW QO. Wrote the paper: YW QO.