About the Authors

Andrew J. Olaharski

andrew.olaharski@roche.com

Affiliation Non Clinical Safety, Roche Palo Alto LLC, Palo Alto, California, United States of America

Nina Gonzaludo

Affiliation Pharma Research Scientific Informatics, Roche Palo Alto LLC, Palo Alto, California, United States of America

Hans Bitter

Affiliation Pharma Research Scientific Informatics, Roche Palo Alto LLC, Palo Alto, California, United States of America

David Goldstein

Affiliation Medicinal Chemistry, Roche Palo Alto LLC, Palo Alto, California, United States of America

Stephan Kirchner

Affiliation Non Clinical Safety, F. Hoffman-La Roche AG, Basel, Switzerland

Hirdesh Uppal

Affiliation Non Clinical Safety, Roche Palo Alto LLC, Palo Alto, California, United States of America

Kyle Kolaja

Affiliation Non Clinical Safety, Roche Palo Alto LLC, Palo Alto, California, United States of America

Competing Interests

All authors are employees of Hoffmann-La Roche and Roche Palo Alto LLC.

Author Contributions

Conceived and designed the experiments: AJO DG KK. Performed the experiments: SK. Analyzed the data: NG HB. Contributed reagents/materials/analysis tools: HU. Wrote the paper: AJO HB.