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Research Article

How Thioredoxin Dissociates Its Mixed Disulfide

  • Goedele Roos mail,

    groos@vub.ac.be (GR); joris.messens@vib-vub.be (JM)

    Affiliations: Department of Molecular and Cellular Interactions, Vlaams Interuniversitair Instituut voor Biotechnologie, Brussels, Belgium, Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium, Brussels Center for Redox Biology, Brussels, Belgium, Algemene Chemie, Vrije Universiteit Brussel, Brussels, Belgium

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  • Nicolas Foloppe,

    Affiliation: Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

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  • Koen Van Laer,

    Affiliations: Department of Molecular and Cellular Interactions, Vlaams Interuniversitair Instituut voor Biotechnologie, Brussels, Belgium, Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium, Brussels Center for Redox Biology, Brussels, Belgium, Algemene Chemie, Vrije Universiteit Brussel, Brussels, Belgium

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  • Lode Wyns,

    Affiliations: Department of Molecular and Cellular Interactions, Vlaams Interuniversitair Instituut voor Biotechnologie, Brussels, Belgium, Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium, Brussels Center for Redox Biology, Brussels, Belgium

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  • Lennart Nilsson,

    Affiliation: Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

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  • Paul Geerlings,

    Affiliation: Algemene Chemie, Vrije Universiteit Brussel, Brussels, Belgium

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  • Joris Messens mail

    groos@vub.ac.be (GR); joris.messens@vib-vub.be (JM)

    Affiliations: Department of Molecular and Cellular Interactions, Vlaams Interuniversitair Instituut voor Biotechnologie, Brussels, Belgium, Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium, Brussels Center for Redox Biology, Brussels, Belgium

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  • Published: August 13, 2009
  • DOI: 10.1371/journal.pcbi.1000461

About the Authors

Goedele Roos, Koen Van Laer, Lode Wyns, Joris Messens
Department of Molecular and Cellular Interactions, Vlaams Interuniversitair Instituut voor Biotechnologie, Brussels, Belgium
Goedele Roos, Koen Van Laer, Lode Wyns, Joris Messens
Structural Biology Brussels, Vrije Universiteit Brussel, Brussels, Belgium
Goedele Roos, Koen Van Laer, Lode Wyns, Joris Messens
Brussels Center for Redox Biology, Brussels, Belgium
Goedele Roos, Koen Van Laer, Paul Geerlings
Algemene Chemie, Vrije Universiteit Brussel, Brussels, Belgium
Nicolas Foloppe, Lennart Nilsson
Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GR JM. Performed the experiments: GR NF KVL. Analyzed the data: GR NF. Wrote the paper: GR NF LW LN PG JM.