Integration of Evolutionary Features for the Identification of Functionally Important Residues in Major Facilitator Superfamily Transporters

Jouhyun Jeon; Jae-Seong Yang; Sanguk Kim

doi:10.1371/journal.pcbi.1000522

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Open Access

Peer-reviewed

Research Article

Integration of Evolutionary Features for the Identification of Functionally Important Residues in Major Facilitator Superfamily Transporters

Jouhyun Jeon,

Affiliation Division of Molecular and Life Science, Pohang University of Science and Technology, Pohang, Korea
⨯
Jae-Seong Yang,

Affiliation School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Korea
⨯
Sanguk Kim

* E-mail: sukim@postech.ac.kr

Affiliations Division of Molecular and Life Science, Pohang University of Science and Technology, Pohang, Korea, School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Korea
⨯

Integration of Evolutionary Features for the Identification of Functionally Important Residues in Major Facilitator Superfamily Transporters

Jouhyun Jeon,
Jae-Seong Yang,
Sanguk Kim

Published: October 2, 2009
https://doi.org/10.1371/journal.pcbi.1000522

About the Authors

Jouhyun Jeon

Affiliation Division of Molecular and Life Science, Pohang University of Science and Technology, Pohang, Korea

Jae-Seong Yang

Affiliation School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Korea

Sanguk Kim

* E-mail: sukim@postech.ac.kr

Affiliations Division of Molecular and Life Science, Pohang University of Science and Technology, Pohang, Korea, School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Korea

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JJ JSY SK. Performed the experiments: JJ. Analyzed the data: JJ JSY SK. Contributed reagents/materials/analysis tools: JJ JSY. Wrote the paper: JJ SK.

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Membrane proteins
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Interaction networks
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Adenosine triphosphatase
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Molecular evolution
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Salt bridges
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Lactose
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Protein structure
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Hydrogen bonding
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