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Research Article

Oxidized Calmodulin Kinase II Regulates Conduction Following Myocardial Infarction: A Computational Analysis

  • Matthew D. Christensen,

    Affiliation: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

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  • Wen Dun,

    Affiliation: Department of Pharmacology, Center for Molecular Therapeutics, Columbia University, New York, New York, United States of America

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  • Penelope A. Boyden,

    Affiliation: Department of Pharmacology, Center for Molecular Therapeutics, Columbia University, New York, New York, United States of America

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  • Mark E. Anderson,

    Affiliations: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America, Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

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  • Peter J. Mohler,

    Affiliations: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America, Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

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  • Thomas J. Hund mail

    thomas-hund@uiowa.edu

    Affiliation: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

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  • Published: December 04, 2009
  • DOI: 10.1371/journal.pcbi.1000583

About the Authors

Matthew D. Christensen, Mark E. Anderson, Peter J. Mohler, Thomas J. Hund
Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America
Mark E. Anderson, Peter J. Mohler
Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America
Wen Dun, Penelope A. Boyden
Department of Pharmacology, Center for Molecular Therapeutics, Columbia University, New York, New York, United States of America

Corresponding Author

Email: thomas-hund@uiowa.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MDC PAB TJH. Performed the experiments: MDC WD PAB TJH. Analyzed the data: MDC MEA PJM TJH. Contributed reagents/materials/analysis tools: MDC WD PAB MEA PJM TJH. Wrote the paper: MDC PAB MEA PJM TJH.