About the Authors

Feng Hong

Affiliation Department of Statistics, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America

Fang Fang

Affiliation Gene Regulation Laboratory, Genome Institute of Singapore, Singapore

Xuming He

Affiliation Department of Statistics, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America

Xiaoyi Cao

Affiliation The Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

Hiram Chipperfield

Affiliation Institute of Medical Biology, Singapore

Dan Xie

Affiliation Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

Wing H. Wong

Affiliation Departments of Statistics, Stanford University, Stanford, California, United States of America

Huck H. Ng

Affiliation Gene Regulation Laboratory, Genome Institute of Singapore, Singapore

Sheng Zhong

szhong@illinois.edu

Affiliations Department of Statistics, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America, Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America, Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SZ. Performed the experiments: FF WHW HHN. Analyzed the data: FH XH XC DX WHW SZ. Contributed reagents/materials/analysis tools: FH FF XH WHW HHN. Wrote the paper: FH SZ.