About the Authors

Bambang S. Adiwijaya

bambang_adiwijaya@vrtx.com

Affiliation Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, United States of America

Eva Herrmann

Affiliation Institute of Biostatistics and Mathematical Modeling, Faculty of Medicine, Johann Wolfgang Goethe University, Frankfurt am Main, Germany

Brian Hare

Affiliation Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, United States of America

Tara Kieffer

Affiliation Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, United States of America

Chao Lin

Affiliation Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, United States of America

Ann D. Kwong

Affiliation Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, United States of America

Varun Garg

Affiliation Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, United States of America

John C. R. Randle

Affiliation Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, United States of America

Christoph Sarrazin

Affiliation Medizinische Klinik 1, J. W. Goethe-University Hospital, Frankfurt am Main, Germany

Stefan Zeuzem

Affiliation Medizinische Klinik 1, J. W. Goethe-University Hospital, Frankfurt am Main, Germany

Paul R. Caron

Affiliation Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, United States of America

Competing Interests

BSA, BH, TK, CL, ADK, VG, PRC are employed by Vertex Pharmaceuticals, Incorporated. JCRR was previously employed by Vertex Pharmaceuticals, Incorporated. EH, CS and SZ have received funding from Vertex Pharmaceuticals, Incorporated for other projects. Vertex Pharmaceuticals, Incorporated is the manufacturer of telaprevir.

Author Contributions

Conceived and designed the experiments: TK ADK VG JCRR CS SZ. Performed the experiments: TK CL CS SZ. Analyzed the data: BSA EH BH TK ADK VG JCRR CS SZ PRC. Contributed reagents/materials/analysis tools: BSA. Wrote the paper: BSA EH BH TK ADK VG JCRR SZ PRC.