Advertisement
Research Article

A Model for Genetic and Epigenetic Regulatory Networks Identifies Rare Pathways for Transcription Factor Induced Pluripotency

  • Maxim N. Artyomov,

    Affiliations: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

    X
  • Alexander Meissner,

    Affiliations: Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, Massachusetts, United States of America

    X
  • Arup K. Chakraborty mail

    arupc@mit.edu

    Affiliations: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Ragon Institute of MGH, MIT, and Harvard, Charlestown, Massachusetts, United States of America

    X
  • Published: May 13, 2010
  • DOI: 10.1371/journal.pcbi.1000785

About the Authors

Maxim N. Artyomov, Arup K. Chakraborty
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
Maxim N. Artyomov, Alexander Meissner
Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America
Alexander Meissner
Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, Massachusetts, United States of America
Arup K. Chakraborty
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
Arup K. Chakraborty
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
Arup K. Chakraborty
Ragon Institute of MGH, MIT, and Harvard, Charlestown, Massachusetts, United States of America

Corresponding Author

Email: arupc@mit.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MNA AKC. Performed the experiments: MNA. Analyzed the data: MNA AKC. Contributed reagents/materials/analysis tools: MNA. Wrote the paper: MNA AM AKC.