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Research Article

Does Mutational Robustness Inhibit Extinction by Lethal Mutagenesis in Viral Populations?

  • Eamon B. O'Dea,

    Affiliation: Section of Integrative Biology, The University of Texas at Austin, Austin, Texas, United States of America

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  • Thomas E. Keller,

    Affiliation: Section of Integrative Biology, The University of Texas at Austin, Austin, Texas, United States of America

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  • Claus O. Wilke mail

    cwilke@mail.utexas.edu

    Affiliations: Section of Integrative Biology, The University of Texas at Austin, Austin, Texas, United States of America, Center for Computational Biology and Bioinformatics and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas, United States of America

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  • Published: June 10, 2010
  • DOI: 10.1371/journal.pcbi.1000811

About the Authors

Eamon B. O'Dea, Thomas E. Keller, Claus O. Wilke
Section of Integrative Biology, The University of Texas at Austin, Austin, Texas, United States of America
Claus O. Wilke
Center for Computational Biology and Bioinformatics and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas, United States of America

Corresponding Author

Email: cwilke@mail.utexas.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EBO COW. Performed the experiments: EBO. Analyzed the data: EBO. Contributed reagents/materials/analysis tools: EBO TEK. Wrote the paper: EBO COW.