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Research Article

Plato's Cave Algorithm: Inferring Functional Signaling Networks from Early Gene Expression Shadows

  • Yishai Shimoni equal contributor,

    equal contributor Contributed equally to this work with: Yishai Shimoni, Marc Y. Fink

    Affiliation: Department of Neurology and Center for Translational Systems Biology, Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Marc Y. Fink equal contributor,

    equal contributor Contributed equally to this work with: Yishai Shimoni, Marc Y. Fink

    Affiliation: Department of Neurology and Center for Translational Systems Biology, Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Soon-gang Choi,

    Affiliation: Department of Neurology and Center for Translational Systems Biology, Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Stuart C. Sealfon mail

    stuart.sealfon@mssm.edu

    Affiliation: Department of Neurology and Center for Translational Systems Biology, Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Published: June 24, 2010
  • DOI: 10.1371/journal.pcbi.1000828

About the Authors

Yishai Shimoni, Marc Y. Fink, Soon-gang Choi, Stuart C. Sealfon
Department of Neurology and Center for Translational Systems Biology, Mount Sinai School of Medicine, New York, New York, United States of America

Corresponding Author

Email: stuart.sealfon@mssm.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YS MYF SCS. Performed the experiments: MYF SGC. Analyzed the data: YS MYF. Contributed reagents/materials/analysis tools: YS MYF. Wrote the paper: YS MYF SCS.