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Research Article

Patterns of Subnet Usage Reveal Distinct Scales of Regulation in the Transcriptional Regulatory Network of Escherichia coli

  • Carsten Marr mail,

    carsten.marr@helmholtz-muenchen.de

    Affiliation: Institute for Bioinformatics and Systems Biology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany

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  • Fabian J. Theis,

    Affiliations: Institute for Bioinformatics and Systems Biology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, Institute for Mathematical Sciences, Technische Universität München, Garching, Germany

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  • Larry S. Liebovitch,

    Affiliation: Center for Complex Systems and Brain Sciences, Florida Atlantic University, Boca Raton, Florida, United States of America

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  • Marc-Thorsten Hütt

    Affiliation: Computational Systems Biology, School of Engineering and Science, Jacobs University Bremen, Bremen, Germany

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  • Published: July 01, 2010
  • DOI: 10.1371/journal.pcbi.1000836

About the Authors

Carsten Marr, Fabian J. Theis
Institute for Bioinformatics and Systems Biology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany
Fabian J. Theis
Institute for Mathematical Sciences, Technische Universität München, Garching, Germany
Larry S. Liebovitch
Center for Complex Systems and Brain Sciences, Florida Atlantic University, Boca Raton, Florida, United States of America
Marc-Thorsten Hütt
Computational Systems Biology, School of Engineering and Science, Jacobs University Bremen, Bremen, Germany

Corresponding Author

Email: carsten.marr@helmholtz-muenchen.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CM LSL MTH. Performed the experiments: CM. Analyzed the data: CM FJT MTH. Wrote the paper: CM FJT LSL MTH.