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Research Article

The Effects of Alignment Quality, Distance Calculation Method, Sequence Filtering, and Region on the Analysis of 16S rRNA Gene-Based Studies

  • Patrick D. Schloss mail

    pschloss@umich.edu

    Affiliation: Department of Microbiology & Immunology, The University of Michigan, Ann Arbor, Michigan, United States of America

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  • Published: July 08, 2010
  • DOI: 10.1371/journal.pcbi.1000844

About the Author

Patrick D. Schloss
Department of Microbiology & Immunology, The University of Michigan, Ann Arbor, Michigan, United States of America

Corresponding Author

Email: pschloss@umich.edu

Competing Interests

The author has declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PDS. Performed the experiments: PDS. Analyzed the data: PDS. Contributed reagents/materials/analysis tools: PDS. Wrote the paper: PDS.