About the Authors

Stephen F. Altschul

altschul@ncbi.nlm.nih.gov

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

John C. Wootton

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Elena Zaslavsky

Affiliation Center for Translational Systems Biology and Department of Neurology, Mount Sinai School of Medicine, New York, New York, United States of America

Yi-Kuo Yu

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SFA JCW EZ YKY. Performed the experiments: SFA JCW YKY. Analyzed the data: SFA JCW YKY. Wrote the paper: SFA JCW EZ YKY. Developed mathematical theory: SFA YKY.