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Research Article

Knotted vs. Unknotted Proteins: Evidence of Knot-Promoting Loops

  • Raffaello Potestio,

    Affiliation: SISSA - Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy

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  • Cristian Micheletti mail,

    michelet@sissa.it

    Affiliations: SISSA - Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy, DEMOCRITOS CNR-IOM, Trieste, Italy, Italian Institute of Technology (SISSA unit), Trieste, Italy

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  • Henri Orland

    Affiliation: Institut de Physique Théorique, CEA, Gif-sur-Yvette, France

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  • Published: July 29, 2010
  • DOI: 10.1371/journal.pcbi.1000864

About the Authors

Raffaello Potestio, Cristian Micheletti
SISSA - Scuola Internazionale Superiore di Studi Avanzati, Trieste, Italy
Cristian Micheletti
DEMOCRITOS CNR-IOM, Trieste, Italy
Cristian Micheletti
Italian Institute of Technology (SISSA unit), Trieste, Italy
Henri Orland
Institut de Physique Théorique, CEA, Gif-sur-Yvette, France

Corresponding Author

Email: michelet@sissa.it

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Analyzed the data: RP CM. Wrote the paper: RP CM HO. Conceived and designed the study: RP CM HO. Contributed analysis tools: RP CM. Processed the databases and gathered the data: RP.