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Research Article

Literature Mining for the Discovery of Hidden Connections between Drugs, Genes and Diseases

  • Raoul Frijters,

    Affiliation: Computational Drug Discovery (CDD), Nijmegen Centre for Molecular Life Sciences (NCMLS), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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  • Marianne van Vugt,

    Affiliation: Department of Immune Therapeutics, Schering-Plough, Oss, The Netherlands

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  • Ruben Smeets,

    Affiliation: Department of Immune Therapeutics, Schering-Plough, Oss, The Netherlands

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  • René van Schaik,

    Affiliation: Department of Molecular Design & Informatics, Schering-Plough, Oss, The Netherlands

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  • Jacob de Vlieg,

    Affiliations: Computational Drug Discovery (CDD), Nijmegen Centre for Molecular Life Sciences (NCMLS), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Department of Molecular Design & Informatics, Schering-Plough, Oss, The Netherlands

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  • Wynand Alkema mail

    wynand.alkema@merck.com

    Affiliation: Department of Molecular Design & Informatics, Schering-Plough, Oss, The Netherlands

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  • Published: September 23, 2010
  • DOI: 10.1371/journal.pcbi.1000943

About the Authors

Raoul Frijters, Jacob de Vlieg
Computational Drug Discovery (CDD), Nijmegen Centre for Molecular Life Sciences (NCMLS), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Marianne van Vugt, Ruben Smeets
Department of Immune Therapeutics, Schering-Plough, Oss, The Netherlands
René van Schaik, Jacob de Vlieg, Wynand Alkema
Department of Molecular Design & Informatics, Schering-Plough, Oss, The Netherlands

Corresponding Author

Email: wynand.alkema@merck.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RF RS RvS JdV WA. Performed the experiments: MvV. Analyzed the data: RF. Wrote the paper: RF WA.