Advertisement
Research Article

HIV Promoter Integration Site Primarily Modulates Transcriptional Burst Size Rather Than Frequency

  • Ron Skupsky,

    Affiliation: California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, California, United States of America

    X
  • John C. Burnett,

    Affiliations: Department of Chemical Engineering, University of California, Berkeley, Berkeley, California, United States of America, Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California, United States of America

    Current address: Department of Molecular and Cell Biology, Beckman Research Institute of the City of Hope, Duarte, California, United States of America.

    X
  • Jonathan E. Foley,

    Affiliation: UCB/UCSF Joint-Graduate-Group-in-Bioengineering, University of California, Berkeley, Berkeley, California, United States of America

    X
  • David V. Schaffer mail,

    schaffer@berkeley.edu (DVS); aparkin@lbl.gov (APA)

    Affiliations: California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, California, United States of America, Department of Chemical Engineering, University of California, Berkeley, Berkeley, California, United States of America, Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California, United States of America, Department of Bioengineering, University of California, Berkeley, Berkeley, California, United States of America

    X
  • Adam P. Arkin mail

    schaffer@berkeley.edu (DVS); aparkin@lbl.gov (APA)

    Affiliations: California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, California, United States of America, Department of Bioengineering, University of California, Berkeley, Berkeley, California, United States of America, Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

    X
  • Published: September 30, 2010
  • DOI: 10.1371/journal.pcbi.1000952

About the Authors

Ron Skupsky, David V. Schaffer, Adam P. Arkin
California Institute for Quantitative Biosciences, University of California, Berkeley, Berkeley, California, United States of America
John C. Burnett, David V. Schaffer
Department of Chemical Engineering, University of California, Berkeley, Berkeley, California, United States of America
John C. Burnett, David V. Schaffer
Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California, United States of America
Jonathan E. Foley
UCB/UCSF Joint-Graduate-Group-in-Bioengineering, University of California, Berkeley, Berkeley, California, United States of America
David V. Schaffer, Adam P. Arkin
Department of Bioengineering, University of California, Berkeley, Berkeley, California, United States of America
Adam P. Arkin
Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RS JCB DVS APA. Performed the experiments: JCB JEF. Analyzed the data: RS. Contributed reagents/materials/analysis tools: RS JCB JEF DVS. Wrote the paper: RS JCB JEF DVS APA.