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Research Article

A Scalable Approach for Discovering Conserved Active Subnetworks across Species

  • Raamesh Deshpande equal contributor,

    equal contributor Contributed equally to this work with: Raamesh Deshpande, Shikha Sharma

    Affiliation: Department of Computer Science and Engineering, University of Minnesota - Twin Cities, Minneapolis, Minnesota, United States of America

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  • Shikha Sharma equal contributor,

    equal contributor Contributed equally to this work with: Raamesh Deshpande, Shikha Sharma

    Affiliation: Department of Chemical Engineering, University of Minnesota - Twin Cities, Minneapolis, Minnesota, United States of America

    X
  • Catherine M. Verfaillie,

    Affiliation: Interdepartmental Stem Cell Institute Leuven, Catholic University Leuven, Leuven, Belgium

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  • Wei-Shou Hu,

    Affiliation: Department of Chemical Engineering, University of Minnesota - Twin Cities, Minneapolis, Minnesota, United States of America

    X
  • Chad L. Myers mail

    cmyers@cs.umn.edu

    Affiliation: Department of Computer Science and Engineering, University of Minnesota - Twin Cities, Minneapolis, Minnesota, United States of America

    X
  • Published: December 09, 2010
  • DOI: 10.1371/journal.pcbi.1001028

About the Authors

Raamesh Deshpande, Chad L. Myers
Department of Computer Science and Engineering, University of Minnesota - Twin Cities, Minneapolis, Minnesota, United States of America
Shikha Sharma, Wei-Shou Hu
Department of Chemical Engineering, University of Minnesota - Twin Cities, Minneapolis, Minnesota, United States of America
Catherine M. Verfaillie
Interdepartmental Stem Cell Institute Leuven, Catholic University Leuven, Leuven, Belgium

Corresponding Author

Email: cmyers@cs.umn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RD CLM. Performed the experiments: RD SS. Analyzed the data: RD SS WSH CLM. Contributed reagents/materials/analysis tools: RD. Wrote the paper: RD SS WSH CLM. Contributed to biological interpretation of results: CMV WSH.