About the Authors

Nozomu Yachie

Affiliations Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan, Systems Biology Program, Graduate School of Media and Governance, Keio University, Fujisawa, Japan, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

Rintaro Saito

rsaito@sfc.keio.ac.jp

Affiliations Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan, Systems Biology Program, Faculty of Environment and Information Studies, Keio University, Fujisawa, Japan

Naoyuki Sugiyama

Affiliation Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan

Masaru Tomita

Affiliations Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan, Systems Biology Program, Graduate School of Media and Governance, Keio University, Fujisawa, Japan, Systems Biology Program, Faculty of Environment and Information Studies, Keio University, Fujisawa, Japan

Yasushi Ishihama

Affiliations Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan, PRESTO, Japan Science and Technology Agency, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NY RS MT YI. Performed the experiments: NY NS. Analyzed the data: NY. Wrote the paper: NY RS.